OPIOIDES SINTÉTICOS NO PEPTÍDICOS CON PROPIEDADES INMUNOMODULADORAS Y ANTITUMORALES

Autores/as

  • Diana Caballero-Hernández Departamento de Microbiología e Inmunología, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, (México)
  • Reyes Tamez-Guerra Departamento de Microbiología e Inmunología, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, (México)
  • Cristina Rodríguez-Padilla Departamento de Microbiología e Inmunología, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, (México)
  • Patricia Tamez- Guerra Departamento de Microbiología e Inmunología, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, (México)
  • Richard J. Weber Department of Biomedical and Therapeutic Sciences, UIC College of Medicine, Peoria, IIL (USA)
  • Ricardo Gómez Flores Departamento de Microbiología e Inmunología, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, (México)

Resumen

El diseño y síntesis de opioides no peptídicos con un perfil farmacológico especifico representa un prometedor campo de estudio, así como una fuente de nuevos compuestos con potencial aplicación terapéutica. En este trabajo hemos evaluado una serie de opioides sintéticos no peptídicos por sus propiedades inmunoreguladoras y antitumorales. Los resultados de este estudio apoyan la noción según la cual los opioides sintéticos, en la misma forma que los naturales, poseen propiedades bioreguladoras de importancia. Mas aun, las observaciones obtenidas con el
agonista opioide SNC 80, sugieren para este compuesto un gran potencial clínico como analgésico no inmunosupresor, y/o agente antitumoral.


Palabras clave: SNC80, antiproliferativo, inmunoestimulante, proinflamatorio   SNC80, antiproliferative, immunostimulating, pro-inflammatory

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Publicado

2004-07-10

Cómo citar

Caballero-Hernández, D., Tamez-Guerra, R., Rodríguez-Padilla, C., Tamez- Guerra, P., Weber, R. J., & Gómez Flores, R. (2004). OPIOIDES SINTÉTICOS NO PEPTÍDICOS CON PROPIEDADES INMUNOMODULADORAS Y ANTITUMORALES. RESPYN Revista Salud Pública Y Nutrición, 5(2). Recuperado a partir de https://respyn.uanl.mx/index.php/respyn/article/view/125

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