Ingesta de antioxidantes y su asociación a Cáncer Cervicouterino en mujeres de un Sistema Universitario
DOI:
https://doi.org/10.29105/respyn19.1-3Keywords:
Cáncer cervicouterino, nutrición, antioxidantesAbstract
El Cáncer Cervicouterino es la cuarta causa más común de cáncer en las mujeres a nivel mundial y es la segunda neoplasia más común en mujeres en México. Se sabe que el estado nutricio comprometido está asociado con resultados adversos en pacientes con cáncer. La evidencia científica sugiere que el cáncer se puede atender desde la prevención primaria, favoreciendo la ingesta dietética. Sin embargo, es importante continuar investigado los antioxidantes y vitaminas en la prevención del CaCu. Objetivos. Correlacionar la prevención de cáncer cervical mediante la ingesta dietética vitamina C, zinc. Metodología. Estudio transversal, observacional, correlacional. La muestra se conformó por 202 mujeres participantes a las cuales se les realizo una entrevista nutricional mediante una encuesta de frecuencia de consumo de alimentos y además se les realizo una evaluación antropométrica. En el análisis estadístico se utilizó la prueba T de student. Resultados. Se encontró que la ingesta de zinc y vitamina C es mayor en personas sanas que en mujeres con NIC. Conclusión. Las mujeres deben consumir alimentos que contienen antioxidantes ya que son requeridos en la dieta humana para favorecer la prevención del cáncer.
Antioxidant intake and its association with Cervical Cancer in women of a University System
Cervical cancer is the fourth most common women’s cancers cause worldwide and the second most common neoplasm in Mexico. It is well known that poor nutritional status is associated with adverse outcomes at oncological patients. Scientific evidence suggests that cancer can be attended, favoring dietary intake, from primary attention. By the way, It’s important to continue researching the antioxidants and vitamins role at cervical cancer prevention. Objectives: To correlate Cervical cancer prevention through dietary intake of vitamin c and zinc. Methodology: Observational, correlational and transversal study. The sample was made up by 202 women who had a nutritional interview with a food consumption survey, also and anthropometric evaluation was carried out. In the statistical analysis the Student´s T test was used. Results: The intake of zinc and vitamin C is higher in healthy people tan in women with NIC. Conclusion. Women should consume foods that contain antioxidants as they are required in the human diet to promote cancer prevention.
Downloads
References
Cardonn, T. M. (2017). Prevención y control del cáncer de cuello uterino. Correo Científico Médico, 21(1), 1–10.
Clarke, M. A. (2017). Health Effects of Overweight and Obesity in 195 Countries over 25 Years. The New England Journal of Medicine, 36(12), 1184–1191. https://doi.org/10.1056/NEJMoa1614362 DOI: https://doi.org/10.1056/NEJMoa1614362
Clarke, M. A., Fetterman, B., Cheung, L. C., Wentzensen, N., Gage, J. C., Katki, H. A., … Schiffman, M. (2018). Epidemiologic evidence that excess body weight increases risk of cervical cancer by decreased detection of precancer. Journal of Clinical Oncology, 36(12), 1184–1191. https://doi.org/10.1200/JCO.2017.75.3442 DOI: https://doi.org/10.1200/JCO.2017.75.3442
Cox, B. A., Crow, W. T., & Johnson, L. (2012). Current nutritional considerations for prevention of cervical cancer. Osteopathic Family Physician, 4(3), 81–84. https://doi.org/10.1016/j.osfp.2011.09.003 DOI: https://doi.org/10.1016/j.osfp.2011.09.003
Crampe-Casnabet, C., Franck, J. eve, Ringa, V., Coeuret-Pellicer, M., Chauvin, P., & Menvielle, G. (2019). Role of obesity in differences in cervical cancer screening rates by migration history. The CONSTANCES survey. Cancer Epidemiology, 58(June 2018), 98–103. https://doi.org/10.1016/j.canep.2018.11.009 DOI: https://doi.org/10.1016/j.canep.2018.11.009
Di Furia, L., Rusciano, M. R., Leonardini, L., Rossi, P., Giammarchi, C., Vittori, E., … Illario, M. (2015). A Nutritional Approach to the Prevention of Cancer: from Assessment to Personalized Intervention. Translational Medicine @ UniSa, 13(6), 33–41. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/27042431%5Cnhttp://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC4811347
Emily, H. (2004). Zinc deficiency, DNA damage and cancer risk. Journal of Nutritional Biochemistry, 15(10), 572–578. https://doi.org/10.1016/j.jnutbio.2004.07.005 DOI: https://doi.org/10.1016/j.jnutbio.2004.07.005
Feng, Y.-H. (2015). The association between obesity and gynecological cancer. Gynecology and Minimally Invasive Therapy, 4, 102–105. https://doi.org/10.1158/1055-9965.EPI-16-0940.Excess
Feng, Y. H. (2015). The association between obesity and gynecological cancer. Gynecology and Minimally Invasive Therapy, 4(4), 102–105. https://doi.org/10.1016/j.gmit.2015.03.003 DOI: https://doi.org/10.1016/j.gmit.2015.03.003
Fernández, E., Gallus, S., & La Vecchia, C. (2006). Nutrition and cancer risk: An overview. Journal of the British Menopause Society, 12(4), 139–142. https://doi.org/10.1258/136218006779160481 DOI: https://doi.org/10.1258/136218006779160481
García-Closas, R., Castellsagué, X., Bosch, X., & González, C. A. (2005). The role of diet and nutrition in cervical carcinogenesis: A review of recent evidence. International Journal of Cancer, 117(4), 629–637. https://doi.org/10.1002/ijc.21193 DOI: https://doi.org/10.1002/ijc.21193
Giuliano, A. R., Siegel, E. M., Roe, D. J., Ferreira, S., Luiza Baggio, M., Galan, L., … Franco, E. L. (2003). Dietary Intake and Risk of Persistent Human Papillomavirus (HPV) Infection: The Ludwig‐McGill HPV Natural History Study. The Journal of Infectious Diseases, 188(10), 1508–1516. https://doi.org/10.1086/379197 DOI: https://doi.org/10.1086/379197
Gröber, U. (2009). Antioxidants and other micronutrients in complementary oncology. Breast Care, 4(1), 13–20. https://doi.org/10.1159/000194972 DOI: https://doi.org/10.1159/000194972
Hwang, J. H., Lee, J. K., Kim, T. J., & Kim, M. K. (2010). The association between fruit and vegetable consumption and HPV viral load in high-risk HPV-positive women with cervical intraepithelial neoplasia. Cancer Causes and Control, 21(1), 51–59. https://doi.org/10.1007/s10552-009-9433-9 DOI: https://doi.org/10.1007/s10552-009-9433-9
Jaimes, E., Reyes, D. Y., Beltrán, Y. L., González, A., López, C. E., & Gómez, E. M. (2018). Nutritional status in patients with cervical cancer at hospital admission. Revista Chilena de Nutrición, 46(1), 6–10. https://doi.org/10.4067/s0717-75182019000100006 DOI: https://doi.org/10.4067/S0717-75182019000100006
Jiang, B., Xiao, S., Khan, M. A., & Xue, M. (2013). Defective antioxidant systems in cervical cancer. Tumor Biology, 34(4), 2003–2009. https://doi.org/10.1007/s13277-013-0804-1 DOI: https://doi.org/10.1007/s13277-013-0804-1
Labani L. (2009). Food consumption pattern in cervical carcinoma patients and controls. Indian J Med Paediatr Oncol., 30(2), 71–75. https://doi.org/10.4103/0971-5851.60051 DOI: https://doi.org/10.4103/0971-5851.60051
Lee, J. K., & So, K. A. (2013). Mild Obesity, Physical Activity, Calorie Intake, and the Risks of Cervical Intraepithelial Neoplasia and Cervical Cancer. PLoS ONE, 8(6). https://doi.org/10.1371/journal.pone.0066555 DOI: https://doi.org/10.1371/journal.pone.0066555
Manju, V., Sailaja, J. K., & Nalini, N. (2002). Circulating lipid peroxidation and antioxidant status in cervical cancer patients: A case-control study. Clinical Biochemistry, 35(8), 621–625. https://doi.org/10.1016/S0009-9120(02)00376-4 DOI: https://doi.org/10.1016/S0009-9120(02)00376-4
MORALES, P. K. (2016). Encuesta Nacional de Salud y Epidemiología de Medio Camino 2016. Informe final de resultados. Resultados Nacionales, 2016, 1–149. Retrieved from https://www.gob.mx/cms/uploads/attachment/file/209093/ENSANUT.pdf
Nawal, M. (2009). Cervical Cancer: A Preventable Death. REVIEWS IN OBSTETRICS & GYNECOLOGY, 2(4).
Ortiz, A. L. A. (2016). Deficiencia de micronutrientes en la dieta del paciente con lesiones precancerosas del cérvix de una clínica de colposcopía en Ciudad Juárez, México. Nutricion Hospitalaria, 33(4), 941–947. DOI: https://doi.org/10.20960/nh.396
Patel, A., Pathak, Y., Patel, J., & Sutariya, V. (2018). Role of nutritional factors in pathogenesis of cancer. Food Quality and Safety, 2(1), 27–36. https://doi.org/10.1093/fqsafe/fyx033 DOI: https://doi.org/10.1093/fqsafe/fyx033
Paul A Cohen, Anjua Jhingran, Ana Oaknin, L. D. (2019). Cervical cancer. Lancet, (393), 169–182. Retrieved from http://jcp.bmj.com/content/55/4/241.abstract DOI: https://doi.org/10.1016/S0140-6736(18)32470-X
Petignat, P., & Roy, M. (2007). Diagnosis and management of cervical cancer. British Medical Journal, 335(7623), 765–768. https://doi.org/10.1136/bmj.39337.615197.80 DOI: https://doi.org/10.1136/bmj.39337.615197.80
Rock, C. L., Michael, C. W., Reynolds, R. K., & Ruffin, M. T. (2000). Prevention of cervix cancer. Critical Reviews in Oncology/Hematology, 33(3), 169–185. https://doi.org/10.1016/S1040-8428(99)00073-6 DOI: https://doi.org/10.1016/S1040-8428(99)00073-6
Siegel, E. M., Salemi, J. L., Villa, L. L., Ferenczy, A., Franco, E. L., & Giuliano, A. R. (2010). Dietary consumption of antioxidant nutrients and risk of incident cervical intraepithelial neoplasia. Gynecologic Oncology, 118(3), 289–294. https://doi.org/10.1016/j.ygyno.2010.05.022 DOI: https://doi.org/10.1016/j.ygyno.2010.05.022
Srivastava, A., Srivastava, S., Natu, S., Gupta, A., Pal, K., Singh, U., … Goel, M. (2009). Lipid peroxidation and antioxidants in different stages of cervical cancer: Prognostic significance. Indian Journal of Cancer, 46(4), 297. https://doi.org/10.4103/0019-509x.55549 DOI: https://doi.org/10.4103/0019-509X.55549
Tomita, L. Y., Longatto Filho, A., Costa, M. C., Avilla Andreoli, M. A., Villa, L. L., Franco, E. L., & Cardoso, M. A. (2010). Diet and serum micronutrients in relation to cervical neoplasia and cancer among low-income Brazilian women. International Journal of Cancer, 126(3), 703–714. https://doi.org/10.1002/ijc.24793 DOI: https://doi.org/10.1002/ijc.24793
Vu, M., Yu, J., Awolude, O. A., & Chuang, L. (2018). Cervical cancer worldwide. Current Problems in Cancer, 42(5), 457–465. https://doi.org/10.1016/j.currproblcancer.2018.06.003 DOI: https://doi.org/10.1016/j.currproblcancer.2018.06.003
Downloads
Published
How to Cite
Issue
Section
License
The rights of the work belong to the author or authors, however, by sending it for publication in the Public Health and Nutrition Magazine of the Faculty of Public Health and Nutrition of the Autonomous University of Nuevo León, they grant the right for its first publication in between electronic, and possibly, in print to the Public Health and Nutrition Magazine. The license used is the Creative Commons attribution, which allows third parties to use what is published whenever the authorship of the work is mentioned and the first publication that is in the Public Health and Nutrition Magazine. Likewise, the author or authors will take into account that it will not be allowed to send the publication to any other journal, regardless of the format. The authors will be able to make other independent and additional contractual agreements for the non-exclusive distribution of the version of the article published in the Public Health and Nutrition Magazine (e.g., institutional repository or publication in a book) provided they clearly state that The work was published for the first time in the Public Health Magazine, Magazine of the Faculty of Public Health and Nutrition of the Autonomous University of Nuevo León.