Food components, mood and their relationship with the immune system in COVID-19.
DOI:
https://doi.org/10.29105/respyn20.4-7Keywords:
Covid-19, compuestos bioactivos, estado de ánimo, sistema inmuneAbstract
Introduction: The SARS-CoV-2 that causes Covid-19 not only affects the immune system, but also confinement has a great impact on the mental and physiological health of the population. Objective: To describe bioactive compounds of food that improves mood and their influence on strengthening the immune system of the population, during the Covid-19 pandemic. Material and method: Databases such as Google Scholar and PubMed (MEDLINE) were consulted, and original and review articles were included. Results: The bioactive components present in food such as probiotics, tryptophan, L-Theanine improve mood (sadness, anger, anguish), even can reduce levels of stress, anxiety and depression. Probiotics, L-Theanine, antioxidants such as vitamin C, tryptophan and fat-soluble vitamins (A, D and E) showed a positive impact on the immune system. Conclusion: According to our review, the main compounds in promoting a calm and relax mood are tryptophan, L-Theanine and polyphenols found in Blueberries and Concord class purple grapes among others. Lactobacillus probiotics and Bifidobacterium probiotics improve anxiety and depression. Also, it has been studied the effect in the immune response of vitamins A, D, E and C, such as Lactobacillus probiotics. Lastly, probiotics and L-Theanine stand out in improving mood and immune response.
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References
Anglin, R., Samaan, Z., Walter, S., & McDonald, S. (2013). Vitamin D deficiency and depression in adults: Systematic review and meta-analysis. Br J Psychiatry, 202(2), 100-107. doi:10.1192/bjp.bp.111.106666 DOI: https://doi.org/10.1192/bjp.bp.111.106666
Akkasheh, G., Kashani-Poor, Z., Tajabadi-Ebrahimi, M., Jafari, P., Akbari, H., et al. (2016). Clinical and metabolic response to probiotic administration in patients with major depressive disorder. Nutrition. 32(3), 315-320. doi: 10.1016/j.nut.2015.09.003 DOI: https://doi.org/10.1016/j.nut.2015.09.003
Asmundson, G. J., Paluszek, M. M., Landry, C. A., Rachor, G. S., McKay, D., & Taylor, S. (2020). Do pre-existing anxiety-related and mood disorders differentially impact COVID-19 stress responses and coping?. J Anxiety Disord. 74, 102271. doi.org/10.1016/j.jiph.2020.06.021 DOI: https://doi.org/10.1016/j.janxdis.2020.102271
Berggren, A., Lazou-Ahrén, I., Larsson, N., Önning, G. (2011). Randomised, double-blind and placebo-controlled study using new probiotic lactobacilli for strengthening the body immune defence against viral infections. Eur J Nutr, 50(3), 203-10. doi: 10.1007/s00394-010-0127-6 DOI: https://doi.org/10.1007/s00394-010-0127-6
Bizzaro, G., Antico, A., Fortunato, A., & Bizzaro, N. (2017). Vitamin D and Autoimmune Diseases: Is Vitamin D Receptor (VDR) Polymorphism the Culprit?. Isr Med Assoc J : IMAJ, 19(7), 438–443. PMID: 28786260
Bravo, R., Matito, S., Cubero, J., Paredes, S. D., Franco, L., Rivero, M., Rodríguez, A. B., & Barriga, C. (2013). Tryptophan-enriched cereal intake improves nocturnal sleep, melatonin, serotonin, and total antioxidant capacity levels and mood in elderly humans. Age (Dordrecht, Netherlands), 35(4), 1277–1285. doi.org/10.1007/s11357-012-9419-5 DOI: https://doi.org/10.1007/s11357-012-9419-5
Butlera, M. J., & Barrientos, R. M. (2020). The impact of nutrition on COVID-19 susceptibility and long-term consequences. Brain Behav Immun, 87, 53–54. doi.org/10.1016/j.bbi.2020.04.040 DOI: https://doi.org/10.1016/j.bbi.2020.04.040
Carr, A. C., & Maggini, S. (2017). Vitamin C and Immune Function. Nutrients, 9(11), 1211. doi.org/10.3390/nu9111211 DOI: https://doi.org/10.3390/nu9111211
Debelo, H., Novotny, J. A., & Ferruzzi, M. G. (2017). Vitamin A. Advances in Nutrition: An International Review Journal, 8(6), 992-994. doi.org/10.3945/an.116.014720 DOI: https://doi.org/10.3945/an.116.014720
Díaz-Castrillón, F. J., & Toro-Montoya, A. I. (2020). SARS-CoV-2/COVID-19: el virus, la enfermedad y la pandemia. Med Lab, 24(3), 183-205. doi.org/10.36384/01232576.268 DOI: https://doi.org/10.36384/01232576.268
Dragoş, D. y Tănăsescu, M. D. (2010). The effect of stress on the defense systems. J Med Life. 3(1), 10-18. PMID: 20302192
Đogaš, Z., Kalcina, L. L., Dodig, I. P., Demirović, S., Madirazza, K., Valić, M., & Pecotić, R. (2020). The effect of COVID-19 lockdown on lifestyle and mood in Croatian general population: a cross-sectional study. Croat Med J. 61(4), 309. doi: 10.3325 / cmj.2020.61.309 DOI: https://doi.org/10.3325/cmj.2020.61.309
Dubey, S., Biswas, P. Ghosh, R. Chattarjee, S. Dubey, M. J., Chatterjee, S., Lahiri, D., Lavie, C. J. (2020). Psychosocial impact of COVID-19. Diabetes Metab Syndr, 14(5), 779-788. doi:10.1016/j.dsx.2020.05.035 DOI: https://doi.org/10.1016/j.dsx.2020.05.035
Gao, J., Xu, K., Liu, H., Liu, G., Bai, M., Peng, C., Li, T., Yin, Y. (2018). Impact of the Gut Microbiota on Intestinal Immunity Mediated by Tryptophan Metabolism. Front Cell Infect Microbiol, 6,8-13. doi: 10.3389/fcimb.2018.00013 DOI: https://doi.org/10.3389/fcimb.2018.00013
Goncalves-Mendes, N., Talvas, J., Dualé, C., Guttmann, A., Corbin, V., et al. (2019). Impact of Vitamin D Supplementation on Influenza Vaccine Response and Immune Functions in Deficient Elderly Persons: A Randomized Placebo-Controlled Trial. Front Immunol, 10; 65. doi.org/10.3389/fimmu.2019.00065 DOI: https://doi.org/10.3389/fimmu.2019.00065
Haskell-Ramsay, C. F., Stuart, R. C., Okello, E. J., & Watson, A. W. (2017). Cognitive and mood improvements following acute supplementation with purple grape juice in healthy young adults. Eur J Nutr, 56(8), 2621–2631. doi.org/10.1007/s00394-017-1454-7 DOI: https://doi.org/10.1007/s00394-017-1454-7
Hemila, H. (2016). Vitamin E administration may decrease the incidence of pneumonia in elderly males. Clinical Interventions in Aging, Volume 11, 1379–1385. doi.org/10.2147/cia.s114515 DOI: https://doi.org/10.2147/CIA.S114515
Hornsby, E., Pfeffer, P. E., Laranjo, N., Cruikshank, W., Tuzova, M., Litonjua, A. A., Weiss, S. T., Carey, V. J., O’Connor, G., & Hawrylowicz, C. (2018). Vitamin D supplementation during pregnancy: Effect on the neonatal immune system in a randomized controlled trial. J Allergy Clin Immunol, 141(1), 269-278.e1. doi.org/10.1016/j.jaci.2017.02.039 DOI: https://doi.org/10.1016/j.jaci.2017.02.039
Infusino, F., Marazzato, M., Mancone, M., Fedele, F., Mastroianni, et al. (2020). Diet Supplementation, Probiotics, and Nutraceuticals in SARS-CoV-2 Infection: A Scoping Review Nutrients. 12(6), 1718. doi.org/10.3390/nu12061718 DOI: https://doi.org/10.3390/nu12061718
Ingram, J., Maciejewski, G., & Hand, C. J. (2020). Changes in diet, sleep, and physical activity are associated with differences in negative mood during COVID-19 lockdown. Front Psychol. 11, 2328. doi.org/10.3389/fpsyg.2020.588604 DOI: https://doi.org/10.3389/fpsyg.2020.605118
Jaatinen, N., Korpela, R., Poussa, T., Turpeinen, A., Mustonen, S., Merilahti, J., Peuhkuri, K., (2014). Effects of daily intake of yoghurt enriched with bioactive components on chronic stress responses: a double-blinded randomized controlled trial. Int J Food Sci Nutr, 65(4), 507–514. doi: 10.3109/09637486.2014.880669 DOI: https://doi.org/10.3109/09637486.2014.880669
Jenkins, T. A., Nguyen, J. C., Polglaze, K. E., & Bertrand, P. P. (2016). Influence of Tryptophan and Serotonin on Mood and Cognition with a Possible Role of the Gut-Brain Axis. Nutrients, 8(1); 56. doi.org/10.3390/nu8010056 DOI: https://doi.org/10.3390/nu8010056
Khadangi, F., & Azzi, A. (2019). Vitamin E - The Next 100 Years. IUBMB life, 71(4), 411–415. doi.org/10.1002/iub.1990 DOI: https://doi.org/10.1002/iub.1990
Khalid, S., Barfoot, K. L., May, G., Lamport, D. J., Reynolds, S. A., & Williams, C. M. (2017). Effects of Acute Blueberry Flavonoids on Mood in Children and Young Adults. Nutrients, 9(2), 158. doi.org/10.3390/nu9020158 DOI: https://doi.org/10.3390/nu9020158
Kozłowska, A., Szostak-Wegierek, D. (2014). Flavonoids food sources and health benefits. Rocz Panstw Zakl Hig, 65(2), 79-85.
Kurihara, S., Hiraoka, T., Akutsu, M., Sukegawa, E., Bannai, M., & Shibahara, S. (2010). Effects of (L)-cystine and (L)-theanine supplementation on the common cold: a randomized, double-blind, and placebo-controlled trial. J Amino Acids, 2010, 307475. DOI: 10.4061/2010/307475 DOI: https://doi.org/10.4061/2010/307475
Lewis, E. D., Meydani, S. N., & Wu, D. (2018). Regulatory role of vitamin E in the immune system and inflammation. IUBMB Life, 71(4), 487-494. doi.org/10.1002/iub.1976 DOI: https://doi.org/10.1002/iub.1976
Lindseth, G., Helland, B. y Caspers, J., (2015). The Effects of Dietary Tryptophan on Affective Disorders. Arch Psychiatr Nurs, 29(2), 102-7. doi:10.1016/j.apnu.2014.11.008 DOI: https://doi.org/10.1016/j.apnu.2014.11.008
Marsland, B.J. (2016). Regula la inflamación con metabolitos microbianos . Nat Medicina. 22 , 581–583. 10.1038 / nm.4117 DOI: https://doi.org/10.1038/nm.4117
Marsh, W. K., Penny, J. L., & Rothschild, A. J. (2017). Vitamin D supplementation in bipolar depression: A double blind placebo controlled trial. J Psychiatr Res, 95, 48–53. doi.org/10.1016/j.jpsychires.2017.07.021 DOI: https://doi.org/10.1016/j.jpsychires.2017.07.021
Medlineplus. (2020). El estrés y su salud. https://medlineplus.gov/spanish/ency/article/003211.htm#:~:text=El%20estr%C3%A9s%20es%20un%20sentimiento,a%20un%20desaf%C3%ADo%20o%20demanda.
Naranjo-Pereira, M. L. (2009). Una revisión teórica sobre el estrés y algunos aspectos relevantes de éste en el ámbito educativo. Rev Educación: 33 (2), 171-190. DOI 10.15517/REVEDU.V33I2.511 DOI: https://doi.org/10.15517/revedu.v33i2.511
Pérez-Fuentes, M. D. C., Molero Jurado, M. D. M., Martos Martínez, Á., & Gázquez Linares, J. J. (2020). Threat of COVID-19 and emotional state during quarantine: Positive and negative affect as mediators in a cross-sectional study of the Spanish population. PloS one, 15(6). doi.org/10.1371/journal.pone.0235305 DOI: https://doi.org/10.1371/journal.pone.0235305
Pincikova, T., Paquin-Proulx, D., Sandberg, J. K., Flodström-Tullberg, M., & Hjelte, L. (2017). Vitamin D treatment modulates immune activation in cystic fibrosis. Clinical & Experimental Immunology, 189(3), 359–371. doi.org/10.1111/cei.12984 DOI: https://doi.org/10.1111/cei.12984
Sakamoto, F., Pereira, R., Bueno, A., Santos, H. (2019). Psychotropic effects of L-theanine and its clinical properties: From the management of anxiety and stress to a potential use in schizophrenia. Pharmacol Res, 147. doi.org/10.1016/j.phrs.2019.104395 DOI: https://doi.org/10.1016/j.phrs.2019.104395
Shakoor, H., Feehan, J., Al Dhaheri, A. S., Ali, H. I., Platat, C., Ismail, L. C., Stojanovska, L. (2021). Immune-boosting role of vitamins D, C, E, zinc, selenium and omega-3 fatty acids: Could they help against COVID-19? Maturitas, 143, 1-9. doi.org/10.1016/j.maturitas.2020.08.003 DOI: https://doi.org/10.1016/j.maturitas.2020.08.003
Steenbergen L, Sellaro R, van Hemert S, Bosch JA, Colzato LS. (2015). A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood. Brain Behav Immun, 48; 258-64. doi.org/10.1016/j.bbi.2015.04.003 DOI: https://doi.org/10.1016/j.bbi.2015.04.003
Speth, M. M., Singer‐Cornelius, T., Oberle, M., Gengler, I., Brockmeier, S. J., & Sedaghat, A. R. (2020). Mood, anxiety and olfactory dysfunction in COVID‐19: evidence of central nervous system involvement?. The Laryngoscope. doi.org/10.1002/lary.28964 DOI: https://doi.org/10.1002/lary.28964
Szodoray P, Horvath IF, Papp G, Barath S, Gyimesi E, Csathy L, Kappelmayer J, Sipka S, Duttaroy AK, Nakken B, Zeher M (2010). The immunoregulatory role of vitamins A, D and E in patients with primary Sjogren's syndrome. Rheumatology (Oxford). 49(2); 211-7. doi: 10.1093/rheumatology/kep374 DOI: https://doi.org/10.1093/rheumatology/kep374
Van-Rheenen, T. E., Meyer, D., Neill, E., Phillipou, A., Tan, E. J., et al. (2020). Mental health status of individuals with a mood-disorder during the COVID-19 pandemic in Australia: Initial results from the COLLATE project. Pharmacol Res. 275; 69–77. doi.org/10.1016/j.jad.2020.06.037 DOI: https://doi.org/10.1016/j.jad.2020.06.037
Wang, C., Pan, R., Wan, X., Tan, Y., Xu, L., et al. (2020). Immediate psychological responses and associated factors during the initial stage of the 2019 coronavirus disease (COVID-19) epidemic among the general population in China. Int J Environ Res Public Health, 17(5), 1729. Doi: 10.3390 / ijerph17051729 DOI: https://doi.org/10.3390/ijerph17051729
Waqas Khan, H. M., Parikh, N., Megala, S. M., & Predeteanu, G. S. (2020). Unusual Early Recovery of a Critical COVID-19 Patient After Administration of Intravenous Vitamin C. Am J Case Rep, 21. doi.org/10.12659/ajcr.925521 DOI: https://doi.org/10.12659/AJCR.925521
White, D. J., de Klerk, S., Woods, W., Gondalia, S., Noonan, C., & Scholey, A. B. (2016). Anti-Stress, Behavioural and Magnetoencephalography Effects of an L-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial. Nutrients, 8(1), 53. doi.org/10.3390/nu8010053 DOI: https://doi.org/10.3390/nu8010053
Xu D. P., Li Y., Meng X., Zhou T., Zhou Y., et al. (2017). Natural Antioxidants in Foods and Medicinal Plants: Extraction, Assessment and Resources. Int J Mol Sci, 18(1), 96. doi: 10.3390/ijms18010096 DOI: https://doi.org/10.3390/ijms18010096
Yan, F. y Polk, DB (2011). Probiotics and immune health. Opinión actual en gastroenterología, 27(6), 496–501. doi.org/10.1097/MOG.0b013e32834baa4d DOI: https://doi.org/10.1097/MOG.0b013e32834baa4d
Yoto, A., Motoki, M., Murao, S., Yokogoshi. (2012). Effects of L-theanine or caffeine intake on changes in blood pressure under physical and psychological stresses. J Physiol Anthropol, 31(1), 1-9. doi: 10.1186/1880-6805-31-28 DOI: https://doi.org/10.1186/1880-6805-31-28
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Copyright (c) 2021 Leticia Interián-Gómez, Sara Elena Aguila-Gutiérrez, Katia Marisol Esquivias-López, Victoria Alejandra Pulido-De la Cruz, Nestor Joshue Silva-Arzola, Karina Gonzalez-Becerra
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