Growth and development in infants with a history of hypoxic-ischemic encephalopathy
DOI:
https://doi.org/10.29105/respyn23.2-787Keywords:
Hypoxic ischemic encephalopathy, Therapeutic hypothermia, Child growth and developmentAbstract
Introduction: Hypoxic-ischemic encephalopathy (HIE) represents one of the main causes of childhood mortality and disability, with important repercussions on the areas that make up integral growth and development. Objective: To analyze the relationship between physical growth patterns and development during the first 24 months in infants with a history of HIE treated with therapeutic hypothermia (HT). Material and methods: Case review study in a non-random sample of 50 infants with a history of HIE treated with HT. Growth was evaluated through the WHO (2006) and INTERGROWTH-21st standards. To measure development, the Gesell Scale was used, obtaining odds ratios to analyze the association between the variables. Results: Growth alterations and delays in child development were a frequent condition throughout the follow-up in the study cases. Statistically significant associations were observed between intrauterine growth restriction (OR=5.00; 95% CI: 1.36-18.34), the trends of decrease in the growth line in the weight for age indicator (OR=10.0; 95% CI: 1.78- 56.15) and the prevalence of moderate and severe developmental delay. Conclusion: Infants with growth impairment have a higher prevalence of moderate and severe developmental delays during the first months of life.
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