Ketogenic diet as an alternative in the treatment of obesity: a bibliographic review study.
DOI:
https://doi.org/10.29105/respyn20.3-6Keywords:
Ketogenic diet, ketone bodies, obesityAbstract
Introduction: There is great interest in the use of the ketogenic diet as an alternative to the treatment of obesity, which has raised the need for health professionals to reexamine the possible benefits of this eating style. Objective: To evaluate the information of the different applications of ketogenic diets in the treatment of obesity through scientific publications. Material and method: Three databases were used (PubMed, Google Scholar, and Clinical Trials). They were combined with logical operators and terms such as ketogenic diet, obesity, ketone bodies, among others. They were combined with logical operators such as ketolysis, fatty acid oxidation, hormonal regulation, satiety and exercise. Results: Twenty-three articles containing randomized clinical trials and animal experiments were considered for the review. The excluded articles did not meet the criteria for levels of evidence and the PRISMA guideline. Conclusions: Although the many benefits of ketogenic diets have been demonstrated, the use should be accompanied by dietary advice and not overuse. The evolutionary model of nutrition is to integrate and individualize the various dietary factors that can contribute to improving the long-term lifestyle.
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Bodensteiner, J. (2009). Commentary on “Optimal clinical management of children receiving the ketogenic diet: Recommendations of the international ketogenic diet study group”. Epilepsia, 50(2), 327. https://doi.org/10.1111/j.1528-1167.2008.01869.x DOI: https://doi.org/10.1111/j.1528-1167.2008.01869.x
Borruel Abadía, M., Moreno Sancho, M. L., Carrera Juliá, S., & Drehmer Rieger, E. (2020). Comparación entre el efecto de la dieta cetogénica y la dieta alta en hidratos de carbono en el aumento de la masa y la fuerza muscular. Nereis. Interdisciplinary Ibero-American Journal of Methods, Modelling and Simulation., (12), 127–135. https://doi.org/10.46583/nereis_2020.12.476 DOI: https://doi.org/10.46583/nereis_2020.12.476
Calzada, R., Altamirao, N., & Ruíz, M. (2008). Reguladores neuroendocrinos y gastrointestinales del apetito y la saciedad. Boletín médico del Hospital Infantil de México, 65(6), 1146–1665. Recuperado de http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1665-11462008000600007&lng=es&tlng=es.
Castaldo, G., Palmieri, V., Galdo, G., Castaldo, L., Molettieri, P., Vitale, A., & Monaco, L. (2016). Aggressive nutritional strategy in morbid obesity in clinical practice: Safety, feasibility, and effects on metabolic and haemodynamic risk factors. Obesity Research & Clinical Practice, 10(2), 169–177. https://doi.org/10.1016/j.orcp.2015.05.001 DOI: https://doi.org/10.1016/j.orcp.2015.05.001
Comeras, L. B., Herzog, H., & Tasan, R. O. (2019). Neuropeptides at the crossroad of fear and hunger: a special focus on neuropeptide Y. Annals of the New York Academy of Sciences, 1455(1), 59–80. https://doi.org/10.1111/nyas.14179 DOI: https://doi.org/10.1111/nyas.14179
Corrêa P, R., & Cardoso de AP, M. (2019). Ketogenic diets in weight loss: a systematic review under physiological and biochemical aspects of nutrition. Revista chilena de nutrición, 46(5), 606–613. https://doi.org/10.4067/s0717-75182019000500606 DOI: https://doi.org/10.4067/S0717-75182019000500606
Covarrubias, P., Aburto, M., & Sámano, F. (2013). Dietas cetogénicas en el tratamiento del sobrepeso y la obesidad. Nutrición clínica y dieta hospitalaria, 33(2), 98–111. https://doi.org/10.12873/332cetogenicas
Cox, P., Kirk, T., & Ashmore, T. (2016). Nutritional Ketosis Alters Fuel Preference and Thereby Endurance Performance in Athletes. Cell Metabolism, 24(2), 256–268. https://doi.org/10.1016/j.cmet.2016.07.010 DOI: https://doi.org/10.1016/j.cmet.2016.07.010
Deemer, S. E., Plaisance, E. P., & Martins, C. (2020). Impact of ketosis on appetite regulation—a review. Nutrition Research, 77, 1–11. https://doi.org/10.1016/j.nutres.2020.02.010 DOI: https://doi.org/10.1016/j.nutres.2020.02.010
Evans, M., Mcswiney, F. T., Brady, A. J., & Egan, B. (2019). No Benefit of Ingestion of a Ketone Monoester Supplement on 10-km Running Performance. Medicine & Science in Sports & Exercise, 51(12), 2506–2515. https://doi.org/10.1249/mss.0000000000002065 DOI: https://doi.org/10.1249/MSS.0000000000002065
Grabacka, M., Pierzchalska, M., Dean, M., & Reiss, K. (2016). Regulation of Ketone Body Metabolism and the Role of PPARα. International Journal of Molecular Sciences, 17(12), 2093. https://doi.org/10.3390/ijms17122093 DOI: https://doi.org/10.3390/ijms17122093
Jungas, R. L., Halperin, M. L., & Brosnan, J. T. (1992). Quantitative analysis of amino acid oxidation and related gluconeogenesis in humans. Physiological Reviews, 72(2), 419–448. https://doi.org/10.1152/physrev.1992.72.2.419 DOI: https://doi.org/10.1152/physrev.1992.72.2.419
Kalra, S., Gupta, L., Khandelwal, D., & Gupta, P. (2017). Ketogenic diet in endocrine disorders: Current perspectives. Journal of Postgraduate Medicine, 63(4), 242. https://doi.org/10.4103/jpgm.jpgm_16_17 DOI: https://doi.org/10.4103/jpgm.JPGM_16_17
Longo, R., Peri, C., & Cricrì, D. (2019). Ketogenic Diet: A New Light Shining on Old but Gold Biochemistry. Nutrients, 11(10), 2497. https://doi.org/10.3390/nu11102497 DOI: https://doi.org/10.3390/nu11102497
Martín-Moraleda, E., Delisle, C., & Collado Mateo, D. (2019). Weight loss and body composition changes through ketogenic diet and physical activity: a methodological and systematic review. Nutrición Hospitalaria, 36(5), 1197–1204. https://doi.org/10.20960/nh.02604 DOI: https://doi.org/10.20960/nh.02604
Moreno, B., Crujeiras, A. B., & Bellido, D. (2016). Obesity treatment by very low-calorie-ketogenic diet at two years: reduction in visceral fat and on the burden of disease. Endocrine, 54(3), 681–690. https://doi.org/10.1007/s12020-016-1050-2 DOI: https://doi.org/10.1007/s12020-016-1050-2
Paoli, A. (2014). Ketogenic Diet for Obesity: Friend or Foe? International Journal of Environmental Research and Public Health, 11(2), 2092–2107. https://doi.org/10.3390/ijerph110202092 DOI: https://doi.org/10.3390/ijerph110202092
Paoli, A., Bosco, G., & Camporesi, E. M. (2015). Ketosis, ketogenic diet and food intake control: a complex relationship. Frontiers in Psychology, 6(27), 1–9. https://doi.org/10.3389/fpsyg.2015.00027 DOI: https://doi.org/10.3389/fpsyg.2015.00027
Pérez, J. (2008). Las dietas cetogénicas: beneficios adicionales a la pérdida de peso y efectos secundarios infundados. Archivos Latinoamericanos de Nutrición, 58(4), 323–329. Recuperado de http://ve.scielo.org/scielo.php?script=sci_arttext&pid=S0004-06222008000400001&lng=es&tlng=es.
Puchalska, P., & Crawford, P. A. (2017). Multi-dimensional Roles of Ketone Bodies in Fuel Metabolism, Signaling, and Therapeutics. Cell Metabolism, 25(2), 262–284. https://doi.org/10.1016/j.cmet.2016.12.022 DOI: https://doi.org/10.1016/j.cmet.2016.12.022
Shilpa, J., & Mohan, V. (2018). Ketogenic diets: Boon or bane? Indian Journal of Medical Research, 148(3), 251–253. https://doi.org/10.4103/ijmr.ijmr_1666_18 DOI: https://doi.org/10.4103/ijmr.IJMR_1666_18
Stocker, R. K., Reber Aubry, E., & Bally, L. (2019). Ketogene Diät: evidenzbasierte therapeutische Anwendung bei endokrinologischen Erkrankungen. Praxis, 108(8), 541–553. https://doi.org/10.1024/1661-8157/a003246 DOI: https://doi.org/10.1024/1661-8157/a003246
Sumithran, P., Prendergast, L. A., & Delbridge, E. (2013). Ketosis and appetite-mediating nutrients and hormones after weight loss. European Journal of Clinical Nutrition, 67(7), 759–764. https://doi.org/10.1038/ejcn.2013.90 DOI: https://doi.org/10.1038/ejcn.2013.90
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